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European Palliative Care Research Collaborative

Welcome to the homepage of the EPCRC website.

EPCRC: Improved treatment of pain, depression and fatigue through translation research



The EPCRC (2006-2010) was the first major palliative care project within the Framework Programmes of the EU.

The project engaged 60 co-workers at 11 centres in six European countries.

The EPCRC addressed three main areas in three main symptoms: genetics, assessment and classification, and guidelines; in pain, depression and cachexia.

The EPCRC had close links to the European Association for Palliative Care (EAPC) and the EAPC Research Network. EPCRC workshops were arranged at all EAPC congresses 2007-2010.

Please go to Project Overview in the menu to your left for more information.
 


Guidelines

New European Clinical Guideline: USE OF OPIOID ANALGESICS IN THE TREATMENT OF CANCER PAIN: evidence-based recommendations from the EAPC

The EPCRC Opioid Guidelines Group have produced revised recommendations on the use of opioid analgesics for cancer pain. The work has been led by the EPCRC Work Package 3.1 team coordinated by Professor Augusto Caraceni at the Unit of Palliative Care, Pain Therapy and Rehabilitation of the Fondazione IRCCS Istituto Nazionale dei Tumori in Milan, Italy. However, coworkers across Europe have contributed to the evidence base by conducting the systematic reviews on which the new recommendations are based. The recommendations have been endorsed by the Board of Directors of the European Association for Palliative Care (EAPC).

The final guideline document may be downloaded here. This document is a word-processed web version of the article published in Lancet Oncology in February 2012. A Podcast with a discussion of the updated guidelines is available at the homepage of Lancet Oncology.

The supporting evidence for the updated opioid guidelines consists of 17 systematic reviews that were published in a special issue of Palliative Medicine in July 2011. The table of contents for the July special issue of Palliative Medicine may be accessed here.
Pdf files of all the systematic reviews may be downloaded for personal use from the EAPC website, here.

A patient friendly guideline summary in five European languages may be accessed below.    

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New European Clinical Guideline: THE MANAGEMENT OF DEPRESSION IN PALLIATIVE CARE

The EPCRC Work Package 3.2 team at King's College London have developed a new, European Clinical Guideline on the Mangement of Depression in Palliative Care. This has been a comprehensive process involving expert and public consultations and literature reviews, including a Cochrane review on the use of antidepressants for depression in physically ill people. A journal paper on the guideline was published in the European Journal of Cancer in January 2011.
The full guideline may be accessed below, along with a patient friendly summary in five European languages.    

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New European Guidelines: CLINICAL PRACTICE GUIDELINES ON CANCER CACHEXIA IN ADVANCED CANCER PATIENTS

The EPCRC cachexia work team has produced new European, clinical guidelines on the management of cancer cachexia in advanced cancer patients, with a focus on refractory cachexia. This has been a comprehensive process involving expert and public consultations and literature reviews. The final guideline may be accessed below, together with a patient friendly summary (leaflet) in five European languages. 

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