The EPCRC Opioid Guidelines Group have produced revised recommendations on the use of opioid analgesics for cancer pain. The work has been led by the EPCRC Work Package 3.1 team coordinated by Professor Augusto Caraceni at the Unit of Palliative Care, Pain Therapy and Rehabilitation of the Fondazione IRCCS Istituto Nazionale dei Tumori in Milan, Italy. However, coworkers across Europe have contributed to the evidence base by conducting the systematic reviews on which the new recommendations are based. The recommendations have been endorsed by the Board of Directors of the European Association for Palliative Care (EAPC).
The final guideline document may be downloaded here. This document is a word-processed web version of the article published in Lancet Oncology in February 2012. A Podcast with a discussion of the updated guidelines is available at the homepage of Lancet Oncology.
The supporting evidence for the updated opioid guidelines consists of 17 systematic reviews that were published in a special issue of Palliative Medicine in July 2011. The table of contents for the July special issue of Palliative Medicine may be accessed here.
Pdf files of all the systematic reviews may be downloaded for personal use from the EAPC website, here.
A patient friendly guideline summary in five European languages may be accessed below.